https://nova.newcastle.edu.au/vital/access/ /manager/Index en-au 5 https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:28423 Wed 11 Apr 2018 14:49:25 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:47836 Wed 01 Feb 2023 14:59:49 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:32511 Tue 12 Jun 2018 15:33:14 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:46893 Tue 06 Dec 2022 12:02:26 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:38554 Thu 14 Mar 2024 12:30:04 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:46043 + T cells, and macrophages are significantly elevated in the bronchoalveolar lavage fluid of patients. A set of cytokines and intracellular transduction regulators are associated with asthma exacerbations and are shared across multiple cell clusters, forming a complicated molecular framework. An additional group of core exacerbation-associated modules is activated, including eukaryotic initiation factor 2 signaling, ephrin receptor signaling, and C-X-C chemokine receptor type 4 signaling in the subpopulations of CD8⁺ T cells (C1-a) and monocyte clusters (C7 clusters), which are associated with infection. Conclusion: Our study identified a significant number of severe asthma-associated genes that are differentially expressed by multiple cell clusters.]]> Thu 10 Nov 2022 14:51:33 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:51252 45° for tested four black soils, indicating that atrazine residue had the greatest P-limitation on soil microorganisms. Interestingly, microbial C- and P-limitations with different atrazine concentrations showed a strong linear relationship, especially in Qiqihar and Nongan soils. Atrazine treatment significantly negatively affected microbial metabolic limitation. Soil properties and EES interaction explained up to 88.2% for microbial C-/P-limitation. In conclusion, this study confirms the EES as a useful method in evaluating the effects of pesticides on microbial metabolic limitations.]]> Mon 28 Aug 2023 12:28:34 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:32983 max) and Michaelis constant (K_m) in unpolluted soils were 0.012-0.267 mM h^-1 and 1.34-3.79 mM respectively. The competitive inhibition constant (K_ic) was 0.17-0.70 mM, which was lower than K_m, suggesting higher enzyme affinity for As than for substrate. The ecological doses, ED₁₀ and ED₅₀ (concentration of As that results in 10% and 50% inhibition on enzyme parameter) for inhibition of catalytic efficiency (V_max/K_m) were lower than those for inhibition of enzyme activity at different substrate concentrations. This suggests that the integrated kinetic parameter, catalytic efficiency is substrate concentration independent and more sensitive to As than ALP activity. Thus, catalytic efficiency was proposed as a more reliable indicator than ALP activity for risk assessment of As pollution.]]> Fri 17 Aug 2018 15:44:20 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:47371 Fri 13 Jan 2023 15:04:30 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:51558 Fri 08 Sep 2023 16:00:51 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:49109 2) over alkaline soils (1 < na < 2), and the adsorption process tended to be irreversible (RL close to 0). The solid binding force (kL) of Sb to alkaline soils is less than that of acidic and neutral soils; therefore, alkaline soils pose a higher risk of secondary pollution. Variation partitioning analysis showed that water-soluble Sb was the predominant factor responsible for the observed decrease in DHA. Ecological doses (ED10) based on water-soluble Sb fluctuated from 3.4 to 360 mg kg−1 in soils. Soil properties, such as pH, total phosphorus, amorphous Fe, and clay content, played a crucial role in Sb toxicity to DHA. This study highlighted the importance of water-soluble Sb while evaluating the Sb toxicity in soils. Thus, the study is useful in risk assessment and remediation of Sb-contaminated soils.]]> Fri 05 May 2023 11:32:09 AEST ]]>